منابع مشابه
Peripartum cardiomyopathy: Causes, diagnosis, and treatment.
Peripartum cardiomyopathy is a life-threatening condition of unknown cause that occurs in previously healthy women during the peripartum period. It is characterized by left ventricular dysfunction and symptoms of heart failure that can arise in the last trimester of pregnancy or up to 5 months after delivery. We review its possible causes and how to recognize and manage it.
متن کاملRare etiological causes of Takotsubo cardiomyopathy Regarding “Takotsubo cardiomyopathy after treatment of pulmonary arterial hypertension”
The valuable comments made by Babu et al. are very much appreciated. Babu et al. stress the value of exercise oxygen consumption and oxygen pulse to assess mortality risk.[1,2] Indeed, both CPET parameters were reduced in the presented patient and remained reduced after the start of therapy.[3] Babu et al. hypothesize that the lack of normalization in CPET parameters may have been explained by ...
متن کاملCardiomyocyte Specific Deletion of Crif1 Causes Mitochondrial Cardiomyopathy in Mice
Mitochondria are key organelles dedicated to energy production. Crif1, which interacts with the large subunit of the mitochondrial ribosome, is indispensable for the mitochondrial translation and membrane insertion of respiratory subunits. To explore the physiological function of Crif1 in the heart, Crif1(f/f) mice were crossed with Myh6-cre/Esr1 transgenic mice, which harbor cardiomyocyte-spec...
متن کاملCardiomyocyte-Specific miRNA-30c Over-Expression Causes Dilated Cardiomyopathy
MicroRNAs (miRNAs) regulate many aspects of cellular function and their deregulation has been implicated in heart disease. MiRNA-30c is differentially expressed in the heart during the progression towards heart failure and in vitro studies hint to its importance in cellular physiology. As little is known about the in vivo function of miRNA-30c in the heart, we generated transgenic mice that spe...
متن کاملAberrant sodium influx causes cardiomyopathy and atrial fibrillation in mice.
Increased sodium influx via incomplete inactivation of the major cardiac sodium channel Na(V)1.5 is correlated with an increased incidence of atrial fibrillation (AF) in humans. Here, we sought to determine whether increased sodium entry is sufficient to cause the structural and electrophysiological perturbations that are required to initiate and sustain AF. We used mice expressing a human Na(V...
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ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 2014
ISSN: 0008-6363,1755-3245
DOI: 10.1093/cvr/cvu091.45